Gene profiling of mouse embryonic stem cell subpopulations (CBX11). Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJDB19980
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Two cell surface markers, PECAM1 and SSEA-1, enabled the separation of mouse ES cells into three cell subpopulations. Chimera assay showed that the expression level of PECAM1 was positively correlated with pluripotency of ES cells, while that of SSEA-1 was correlated with the capacity to contribute to the epiblast after blastocyst stage. To identify the key factors for maintenance of pluripotency and for acquisition of competency for differentiation into epiblast cells, we examined gene expression profiles of ES cell subpopulations using microarray analysis.
创建时间:
2025-01-15



