Naquihexcin A, a S‑Bridged Pyranonaphthoquinone Dimer Bearing an Unsaturated Hexuronic Acid Moiety from a Sponge-Derived Streptomyces sp. HDN-10-293

Figshare2016-07-11 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Naquihexcin_A_a_S_Bridged_Pyrano_naphtho_quinone_Dimer_Bearing_an_Unsaturated_Hexuronic_Acid_Moiety_from_a_Sponge-Derived_i_Streptomyces_i_sp_HDN-10-293/3463136

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S-Bridged pyranonaphthoquinone dimers, naquihexcins A and B (1 and 2), together with a related analogue (−)-BE-52440A (3) were obtained from the culture of a sponge-derived Streptomyces sp. HDN-10-293. Naquihexcin A (1) bears a rare unsaturated hexuronic acid moiety, and (−)-BE-52440A (3) has been discovered from natural resources. Compound 3 showed cytotoxicity against NB4 and HL-60 cells, while 1 could inhibit the proliferation of the adriamycin resistant human breast cancer cell line MCF-7 ADM.

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2016-07-11

Naquihexcin A, a S‑Bridged Pyrano­naphtho­quinone Dimer Bearing an Unsaturated Hexuronic Acid Moiety from a Sponge-Derived Streptomyces sp. HDN-10-293

Naquihexcin A, a S‑Bridged Pyranonaphthoquinone Dimer Bearing an Unsaturated Hexuronic Acid Moiety from a Sponge-Derived Streptomyces sp. HDN-10-293