Neutralization of Lyssavirus determined by Rapid Fluorescent Focus Inhibition Test (RFFIT).
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aMean IC50 of triplicates.bMonovalent and bivalent/biparatopic with 15GS linkers run at two different time points, but standards OIE (canine reference serum) 0.5 IU/ml, WHO human reference serum 0.5 IU/ml and WHO human reference serum 6.0 IU/ml were included in all experiments as controls.cPotency compared to monovalent VHH (nM). For the biparatopic constructs, potency increase is based on the mean (nM) of the two monovalent VHH included in the constructs.
创建时间：
2015-12-02
