Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses [Luminex]

ChEBI2022-11-05 更新2026-07-12 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12380 数据链接链接失效反馈

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Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses [Luminex]

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2022-11-05

DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

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PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

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Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.

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B细胞发育

Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated

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Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

细菌癌症疗法

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Bacterial cancer therapy (BCT) is a promising therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is well-studied amongst bacterial vectors due to advantages in genetic modification a

NIAID Data Ecosystem00

Genes in yeast two-hybrid screening.

宿主-病原体相互作用

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Intracellular bacterial pathogens exhibit heterogeneous replication rates within host macrophages, but the mechanisms by which they manipulate host factors for survival remain incompletely understood.

NIAID Data Ecosystem10

Acetyl-CoA Carboxylase-1 Inhibition Increases Regulatory T-Cell Metabolism, Mitochondrial Fusion and Graft-vs-Host Disease Treatment Efficacy [L2_cGvHD]

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移植物抗宿主病治疗

Regulatory T-cells (Treg) are critical for maintaining immune homeostasis, and their adoptive transfer can treat murine inflammatory disorders. In patients, Treg therapies have been variably efficacio

NIAID Data Ecosystem00

Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses [Luminex]

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