Total Synthesis of (−)-Pavidolide B: A Ring Contraction Strategy
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https://figshare.com/articles/dataset/Total_Synthesis_of_-Pavidolide_B_A_Ring_Contraction_Strategy/8344073
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资源简介:
A ring contraction approach for the
total synthesis of (−)-pavidolide
B was developed, which assembles this polycyclic natural product within
13 steps from known chiral alcohol 11. The key features
of the strategy include (a) a double Mukaiyama–Michael addition/elimination,
(b) a ring-closing metathesis, (c) a Wolff rearrangement, and (d)
a late-stage regioselective Schenck ene reaction.
创建时间:
2019-06-21



