Crystal structure of SusG from Bacteroides thetaiotaomicron covalently bound to alpha-1,6 branched pseudo-trisaccharide activity-based probe

Crystal structure of SusG from Bacteroides thetaiotaomicron covalently bound to alpha-1,6 branched pseudo-trisaccharide activity-based probe Descriptor: (1~{R},2~{R},3~{S},4~{R},5~{R},6~{S})-5-(hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2,3,4-triol, (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, ACETATE ION, ... Authors: Pickles, I.B, Moroz, O, Davies, G. Deposit date: 2024-07-04 Release date: 2024-12-11 Last modified: 2025-02-05 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Precision Activity-Based alpha-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes. Angew.Chem.Int.Ed.Engl., 64, 2025

本数据集为来自卵形拟杆菌（Bacteroides thetaiotaomicron）的SusG蛋白晶体结构，该蛋白与α-1,6支链假三糖活性探针共价结合。配体描述：(1R,2R,3S,4R,5R,6S)-5-(羟甲基)-7-氧杂双环[4.1.0]庚烷-2,3,4-三醇、(1S,4S,5R)-6-(羟甲基)环己烷-1,2,3,4,5-五醇、乙酸根离子…… 作者：Pickles I.B.、Moroz O.、Davies G.。沉积日期：2024年7月4日；发布日期：2024年12月11日；最后修改日期：2025年2月5日。实验方法：X射线衍射（分辨率2.65埃）。引用文献：《精准活性α-淀粉酶探针用于直链与支链淀粉降解酶的解析与注释》，Angew.Chem.Int.Ed.Engl., 64, 2025