QIN-PROSTATE-Repeatability

This is a dataset with multiparametric prostate MRI applied in a test-retest setting, allowing to evaluate repeatability of the MRI-based measurements in the prostate. There is very limited data about the repeatability in mpMRI of the prostate, while such information is critical for establishing technical characteristics of mpMRI as imaging biomarker of prostate cancer. Acquisition Protocol: Standard prostate mpMRI protocol implemented at Brigham and Women's Hospital was used in this study. For a given patient, we aimed to maintain similar protocol settings, and used the same scanner hardware and software configurations for both the baseline and repeat examinations, which were acquired within 2 weeks of time. All of the imaging studies were acquired at 3 Tesla magnet strength. Due to the scanner hardware upgrade in the middle of the study, 6 of the patients had baseline and repeat study performed on a GE Signa HDxt platform, software release 15.0_M4A_097.a, while the remaining 7 patients were scanned on a GE Discovery MR750w, software release DV24.0_R01_1344 (General Electric Healthcare, Milwaukee, WI). Transrectal coil within an air-filled balloon (Medrad Inc., Warrendale, PA) was used in all imaging studies. mpMRI protocol included T2-weighted, Diffusion Weighted (DW) (b-values of 0 and 1400 mm/s2) and Dynamic Contrast Enhanced (DCE) sequences. Detailed acquisition parameters are listed in Table 1 of [1]. DWI Apparent Diffusion Coefficient (ADC) and DCE subtract maps (further referred to as SUB; computed as the difference between the phase corresponding to the contrast bolus arrival and the baseline phase) were generated using the scanner software. The imaging data is accompanied by the following types of derived data:

本数据集为应用于重测（test-retest）场景的前列腺多参数磁共振成像（multiparametric prostate MRI, mpMRI）数据集，可用于评估前列腺磁共振成像测量结果的可重复性。目前关于前列腺mpMRI可重复性的公开数据十分有限，而此类信息对于确立mpMRI作为前列腺癌成像生物标志物的技术特性至关重要。采集方案：本研究采用布里格姆妇女医院（Brigham and Women's Hospital）的标准前列腺mpMRI采集协议。对于每位受试者，我们力求保持一致的协议设置，且基线扫描与重测扫描均使用相同的扫描仪硬件与软件配置，两次扫描间隔不超过2周。所有成像数据均采用3特斯拉磁场强度采集。由于研究中期进行了扫描仪硬件升级，其中6位受试者的基线扫描与重测扫描均在通用电气（GE）Signa HDxt平台（软件版本15.0_M4A_097.a）上完成，剩余7位受试者则在GE Discovery MR750w平台（软件版本DV24.0_R01_1344，通用电气医疗集团，威斯康星州密尔沃基市）上完成扫描。所有成像扫描均使用充气气囊式直肠内线圈（Medrad公司，宾夕法尼亚州沃伦代尔市）。本mpMRI协议包含T2加权成像、弥散加权成像（Diffusion Weighted, DW）（b值分别为0和1400 mm/s²）以及动态对比增强（Dynamic Contrast Enhanced, DCE）序列。详细采集参数见参考文献[1]的表1。弥散加权成像的表观弥散系数（Apparent Diffusion Coefficient, ADC）图与DCE减影图（后续简称SUB图，其计算方式为对比剂首达时相与基线时相的信号差值）均通过扫描仪软件生成。本成像数据集附带以下类型的衍生数据：

搜集汇总

背景与挑战

背景概述

QIN-PROSTATE-Repeatability是一个用于评估前列腺多参数MRI测量可重复性的数据集，包含429.3MB的MRI图像及衍生数据（如手动分割和体积测量），属于2D语义分割类别。该数据集对于建立前列腺癌成像生物标志物的技术特性至关重要。