The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates
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The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Farnesyl pyrophosphate synthase, ... Authors: Tsoumpra, M.K, Barnett, B.L, Muniz, J.R.C, Walter, R.L, Ebetino, F.H, von Delft, F, Russell, R.G.G, Oppermann, U, Dunford, J.E. Deposit date: 2013-11-12 Release date: 2014-11-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates To be Published
本数据集研究赖氨酸200与苯丙氨酸239位点的法尼基焦磷酸合酶（Farnesyl Pyrophosphate Synthase，FPPS）突变对其催化活性、晶体结构及含氮双膦酸盐抑制作用的影响。描述符：1,2-乙二醇二(羟乙基)醚、法尼基焦磷酸合酶等。作者：Tsoumpra, M.K.、Barnett, B.L.、Muniz, J.R.C.、Walter, R.L.、Ebetino, F.H.、von Delft, F.、Russell, R.G.G.、Oppermann, U.、Dunford, J.E.。存储日期：2013-11-12；发布日期：2014-11-19；最后修改日期：2023-09-20。实验方法：X射线衍射（2 Å）。引用文献：《赖氨酸200与苯丙氨酸239位点的法尼基焦磷酸合酶（FPPS）突变对其催化活性、晶体结构及含氮双膦酸盐抑制作用的影响》（待发表）
创建时间：
2013-11-12
