Transcription regulators where the predicted activation status is reversed following BW720c exposure.

The predictions of activation or inhibition of transcription regulators are based on the direction of expression of differentially expressed known target genes collated in the IPA database. Cut-off criteria, Z score >2 for activation and <−2 for inhibition. * indicates those predictions that are most significant based on p value. Target gene ratio represents the number of genes expressed in a direction consistent with the prediction over the total number of target genes for that transcription regulator identified in the database. ** SMARCB1 is predicted to be activated at 24 and 48 h as a direct result of parasite inhibition by BW720c.