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Radical-Induced Metal and Solvent-Free Cross-Coupling Using TBAI–TBHP: Oxidative Amidation of Aldehydes and Alcohols with <i>N</i>‑Chloramines via C–H Activation

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NIAID Data Ecosystem2026-03-07 收录
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A solvent-free cross-coupling method for oxidative amidation of aldehydes and alcohols via a metal-free radial pathway has been demonstrated. The proposed methodology uses the TBAI-TBHP combination which efficiently induces metal-free C–H activation of aldehydes under neat conditions at 50 °C or ball-milling conditions at room temperature.

创建时间:
2015-01-02
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