Noninvasive prenatal testing (NIPT) for monogenic disorders has been developed in recent years; however, there are still significant technical and analytical challenges for clinical use. The clinical
Custom-commercial Aedes aegypti array from Agilent, containing 45220 60-mer probes, designed against the AaegL1.1 set of 16k transcripts at the University of California, Irvine.
Values in parentheses indicate percentage of SFP detected/escaped by gene-chip. Table includes SFP data analyzed at estimated 9.5% FDR in CP&LG and 9% FDR in CP&RT dataset. CP = Cypress, LG = LaGrue,