five

Data from: Candidate genes and genetic architecture of symbiotic and agronomic traits revealed by whole-genome, sequence-based association genetics in Medicago truncatula

收藏
DataONE2013-07-12 更新2024-06-27 收录
下载链接:
https://search.dataone.org/view/null
下载链接
链接失效反馈
资源简介:
Genome-wide association study (GWAS) has revolutionized the search for the genetic basis of complex traits. To date, GWAS have generally relied on relatively sparse sampling of nucleotide diversity, which is likely to bias results by preferentially sampling high-frequency SNPs not in complete linkage disequilibrium (LD) with causative SNPs. To avoid these limitations we conducted GWAS with >6 million SNPs identified by sequencing the genomes of 226 accessions of the model legume Medicago truncatula. We used these data to identify candidate genes and the genetic architecture underlying phenotypic variation in plant height, trichome density, flowering time, and nodulation. The characteristics of candidate SNPs differed among traits, with candidates for flowering time and trichome density in distinct clusters of high linkage disequilibrium (LD) and the minor allele frequencies (MAF) of candidates underlying variation in flowering time and height significantly greater than MAF of candidates underlying variation in other traits. Candidate SNPs tagged several characterized genes including nodulation related genes SERK2, MtnodGRP3, MtMMPL1, NFP, CaML3, MtnodGRP3A and flowering time gene MtFD as well as uncharacterized genes that become candidates for further molecular characterization. By comparing sequence-based candidates to candidates identified by in silico 250K SNP arrays, we provide an empirical example of how reliance on even high-density reduced representation genomic makers can bias GWAS results. Depending on the trait, only 30–70% of the top 20 in silico array candidates were within 1 kb of sequence-based candidates. Moreover, the sequence-based candidates tagged by array candidates were heavily biased towards common variants; these comparisons underscore the need for caution when interpreting results from GWAS conducted with sparsely covered genomes.
创建时间:
2013-07-12
用户留言
有没有相关的论文或文献参考?
这个数据集是基于什么背景创建的?
数据集的作者是谁?
能帮我联系到这个数据集的作者吗?
这个数据集如何下载?
点击留言
数据主题
具身智能
数据集  4099个
机构  8个
大模型
数据集  439个
机构  10个
无人机
数据集  37个
机构  6个
指令微调
数据集  36个
机构  6个
蛋白质结构
数据集  50个
机构  8个
空间智能
数据集  21个
机构  5个
5,000+
优质数据集
54 个
任务类型
进入经典数据集
热门数据集

中国区域交通网络数据集

该数据集包含中国各区域的交通网络信息,包括道路、铁路、航空和水路等多种交通方式的网络结构和连接关系。数据集详细记录了各交通节点的位置、交通线路的类型、长度、容量以及相关的交通流量信息。

data.stats.gov.cn 收录

学生课堂行为数据集 (SCB-dataset3)

学生课堂行为数据集(SCB-dataset3)由成都东软学院创建,包含5686张图像和45578个标签,重点关注六种行为:举手、阅读、写作、使用手机、低头和趴桌。数据集覆盖从幼儿园到大学的不同场景,通过YOLOv5、YOLOv7和YOLOv8算法评估,平均精度达到80.3%。该数据集旨在为学生行为检测研究提供坚实基础,解决教育领域中学生行为数据集的缺乏问题。

arXiv 收录

CTD (Comparative Toxicogenomics Database)

CTD是一个综合性的数据库,旨在通过整合基因、化学物质、疾病和环境暴露的数据,来促进对环境因素与人类疾病之间关系的理解。该数据库包括化学物质与基因的相互作用、化学物质与疾病的关联、基因与疾病的关联以及化学物质与环境暴露的关联。CTD还提供数据下载、API访问和在线查询工具。

ctdbase.org 收录

FAOSTAT Agricultural Data

FAOSTAT Agricultural Data 是由联合国粮食及农业组织(FAO)提供的全球农业数据集。该数据集涵盖了农业生产、贸易、价格、土地利用、水资源、气候变化、人口统计等多个方面的详细信息。数据包括了全球各个国家和地区的农业统计数据,旨在为政策制定者、研究人员和公众提供全面的农业信息。

www.fao.org 收录

Fruits-360

一个高质量的水果图像数据集,包含多种水果的图像,如苹果、香蕉、樱桃等,总计42345张图片,分为训练集和验证集,共有64个水果类别。

github 收录