A putative two-component-like signaling pathway in Giardia duodenalis.

A generalized complete two-component signaling pathway cartoon is displayed in grey. Putative structures for hypothetical G. duodenalis proteins are displayed in blue, with accession numbers (GL50803) at right. The genes encoding these hypothetical proteins are down-regulated at the declining phase relative to log and stationary phases, with the exception of the histidine kinase. For each putative G. duodenalis structure, the closest structural match available in the Research Collaboratory for Structural Bioinformatics Protein Data Bank is shown in gold, with the PDB code at right. *single-copy ortholog identified in G. duodenalis assemblages B and E (GiardiaDB.org).