Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium

Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... Authors: Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. Deposit date: 2014-02-03 Release date: 2014-04-23 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014

结核分枝杆菌来源的邻氨基苯甲酸磷酸核糖转移酶（Anthranilate phosphoribosyltransferase）与3-甲基邻氨基苯甲酸、PRPP及镁离子形成的复合物。描述项：1-O-焦膦酰基-5-O-膦酰基-α-D-呋喃核糖（即5-磷酸-α-D-核糖-1-焦磷酸，PRPP）、2-氨基-3-甲基苯甲酸、邻氨基苯甲酸磷酸核糖转移酶……作者：Castell, A、Cookson, T.V.M、Short, F.L、Lott, J.S。提交日期：2014-02-03；发布日期：2014-04-23；最后更新日期：2023-12-27。实验方法：X射线衍射（1.89埃）。引用文献：《替代底物揭示结核分枝杆菌来源的邻氨基苯甲酸磷酸核糖转移酶催化反应的循环机制与关键结合事件》，《Biochem.J.》（生物化学杂志），461卷，2014年。