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The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue

ChEBI2012-02-24 更新2026-07-21 收录

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炎症信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36033 数据链接链接失效反馈

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资源简介：

The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue

应用场景：

创建时间：

2012-02-24

转录组学分析

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GSEA core enrichment - Oxphos - IL-10 immunodepleted vs low LPS plasma. (XLS 61 kb)

NIAID Data Ecosystem70

D- 2-hydroxyglutarate is an immunometabolite that accumulates in macrophages after TLR activation and inhibits inflammatory responses

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巨噬细胞炎症抑制

Macrophages undergo extensive metabolic rewiring upon activation and this serves many roles beyond the production of energy and anabolic building blocks. So-called immunometabolites that accumulate up

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Phagocytosis by macrophages promotes pancreatic β cell mass reduction after parturition in mice

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胰腺β细胞动力学

Original western blot images for Figures 3g, 3i and 3j

NIAID Data Ecosystem20

Pro-survival Lipid Sphingosine-1-Phosphate Metabolically Reprograms T cell to Limit its Anti-Tumor Activity

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T细胞功能调控

Sphingosine 1-phosphate (S1P), a pro-tumor survival bioactive lysophospholipid, generated by sphingosine kinase 1 (SphK1), regulates lymphocyte egress into circulation via transducing S1P receptor 1 (

NIAID Data Ecosystem50

DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

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PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

NIAID Data Ecosystem30

The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue

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