p53 ChIP-seq of primary astrocytes in vitro. p53 ChIP-seq of primary astrocytes in vitro

To investigate the transcriptional regulation by p53 in astrocytes, we performed ChIP-sequencing using p53 antibody (Leica CM-5) or rabbit IgG control in wildtype primary mouse cortical astrocytes. Ov

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ChIP-seq for p53 family

For the identification of direct transcriptional targets of p53 family members.

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Single-cell RNA-seq analysis of p53 knockout primary astrocytes in vitro.. Single-cell RNA-seq analysis of p53 knockout primary astrocytes in vitro.

To investigate the mechansims that underly astrocyte dedifferentiation, we performed single cell RNA sequencing analysis of primary astrocytes after p53 loss and exposure to mitogens, EGF and and FGF.

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