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Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2

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Protein Data Bank Japan2024-02-14 更新2026-03-21 收录
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Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2 Descriptor: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ... Authors: Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M. Deposit date: 2005-01-09 Release date: 2005-12-20 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. Proteins, 62, 2005

克氏锥虫(Trypanosoma cruzi)法尼基二磷酸合酶(farnesyl diphosphate synthase)与利塞膦酸(risedronate)、二甲基烯丙基二磷酸(dmapp)以及镁离子(Mg²+)形成的复合物结构。 成分描述:1-羟基-2-(3-吡啶基)亚乙基双膦酸、二甲基烯丙基二磷酸、镁离子…… 作者:Gabelli S.B.、McLellan J.S.、Montalvetti A.、Oldfield E.、Docampo R.、Amzel L.M. 存档日期:2005-01-09 发布日期:2005-12-20 最后修改日期:2024-02-14 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.95埃(Å) 引用文献:《克氏锥虫法尼基二磷酸合酶的结构与作用机制:对药物设计的启示》,《Proteins》,第62卷,2005年
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2005-01-09
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