Insulin signaling in adipocytes (diabetic condition)

The paper describes insulin signaling in human adipocytes under normal and diabetic states using mathematical models based on experimental data. This model corresponds to insulin signaling under diabetic condition. Insulin signaling under normal condition is represented in WP3634. The model has been converted to GPML using the PathSBML plugin from PathVisio, importing the model BIOMD0000000449 from the BioModels Database directly. The layout has been improved manually.

该论文运用基于实验数据的数学模型，阐述了在正常及糖尿病状态下的人体脂肪细胞中胰岛素信号传导过程。该模型对应于糖尿病条件下的胰岛素信号传导。正常条件下的胰岛素信号传导以WP3634表示。通过PathVisio软件的PathSBML插件，模型已转换为GPML格式，并直接从BioModels数据库导入模型BIOMD0000000449。布局已手动优化。