Supplementary Information for "Nucleoside Phosphorylases Make N7-Xanthosine, a "Non native" Regioisomer of Xanthosine"

This is the external Supplementary Information for our publication "Nucleoside Phosphorylases Make N7-Xanthosine, a "Non native" Regioisomer of Xanthosine". The .pdf file contains the Supplementary Information: author contributions, accessibility statement, experimental procedures, and supplementary items, among others. The .zip file contains the raw data and metadata for all items (supplementary and main text) as well as the calculation results. This includes UV, HPLC, NMR, HRMS, and DFT results. The full set of raw HPLC chromatograms is - unfortunately - only available to us in a proprietary file format but we are happy to share these data upon request. This revised version contains additional UV data on experiments excluding oxidation of xanthine to uric acid as well as additional NMR data on purified N7-xanthosine and reference data for N9-xanthosine and xanthine in D2O. To some extent, this work builds on and borrows from our previous publications on spectral unmixing (https://doi.org/10.3390/mps2030060, https://doi.org/10.1002/cbic.202000204), continuous reaction monitoring (https://doi.org/10.1021/acs.analchem.1c05356), and thermodynamic reaction control (https://doi.org/10.1002/adsc.201901230, https://doi.org/10.5281/zenodo.3568858, https://doi.org/10.1002/cphc.202000901, https://doi.org/10.1021/acscatal.1c02589).