Primary B cell receptor (BCR)/antibody variable region exons are generated by V(D)J recombination with junctional diversification creating immensely diverse antigen contact-encoding CDR3s. While most
BackgroundCarriage of and infection with Streptococcus pneumoniae is known to predominantly induce T helper 17 (Th17) responses in humans, but the types of Th cells showing reactivity towards commensa
aNormal values (median;5th–95th percentile) for 11 healthy adult males [18]. bSignificance from one-tailed t-tests comparing cell counts of the normal healthy males to the brothers' counts: ns p>0.05;
