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Enantioselective Organocatalytic Michael Addition of Nitroalkanes and Other Nucleophiles to β‑Trifluoromethylated Acrylamides

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Enantioselective_Organocatalytic_Michael_Addition_of_Nitroalkanes_and_Other_Nucleophiles_to_Trifluoromethylated_Acrylamides/2426461
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资源简介:
An organocatalytic asymmetric Michael addition of nitroalkanes to trifluoromethylated acrylamides in good yields and with good to excellent diastereoselectivities and excellent enantioselectivities is described. The Michael adducts could be readily transformed into optically pure trifluoromethylated γ-aminobutyric acid 7 in high yields without loss in enantioselectivities.
创建时间:
2013-04-05
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