Enantioselective Organocatalytic Michael Addition of Nitroalkanes and Other Nucleophiles to β‑Trifluoromethylated Acrylamides
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https://figshare.com/articles/dataset/Enantioselective_Organocatalytic_Michael_Addition_of_Nitroalkanes_and_Other_Nucleophiles_to_Trifluoromethylated_Acrylamides/2426461
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资源简介:
An
organocatalytic asymmetric Michael addition of nitroalkanes
to trifluoromethylated acrylamides in good yields and with good to
excellent diastereoselectivities and excellent enantioselectivities
is described. The Michael adducts could be readily transformed into
optically pure trifluoromethylated γ-aminobutyric acid 7 in high yields without loss in enantioselectivities.
创建时间:
2013-04-05



