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Monocytes transition to monocyte-macrophages within the inflamed vasculature via CCR2 on monocytes and endothelial TNFR2

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP360251
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Our study reports the CCR2 dependent functional specialization of monocytes into immature macrophages occurs within the TNF-TNFR2 activated vasculature and establishes a chemokine-based autocrine, feed-forward loop that may aplify the inflammation and renal injury. Overall design: Monocytes and the endothelial cell co-cultures along with monocytes on plastic were harvested and subjected to 10X. Sample populations were stained with Total-Seq A hashtag antibodies #1 - #10. The populations were pooled together and were loaded onto the 10X Chromium controller. Please note that individual sample information is provided in the sample_info.txt
创建时间:
2022-05-22
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