Clinical and biochemical characteristics of COVID(+) and COVID(-) patients with hyperglycemic crisis: a cross-sectional study

A cross-sectional study was conducted with 82 patients admitted to an urban academic medical center in Philadelphia, PA, USA between March 1st and July 30th, 2020. Data were collected by computer query and manual review of electronic health records. Patients met lab criteria for either DKA (serum bicarbonate ≤18 mEq/L, anion gap >10, ketonemia or ketonuria, and arterial pH ≤7.30), or HHS (blood glucose > 33.3 mmol/L and osmolality > 320 mOsm/kg).[7] Mixed DKA-HHS was defined as meeting all criteria for either DKA or HHS with at least 1 criterion for the other diagnosis. Diagnoses were adjudicated by an endocrinologist.