Generation of KRAS knockout pancreatic cancer cell line PANC1
收藏NIAID Data Ecosystem2026-05-01 收录
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We used CRISPR to inactivate mutant KRAS and STAT3 in PANC1 (KRASG12D) pancreatic cancer cell line. Gene expression analysis of KRAS intact vs. knockout cells identified sets of genes involved in protein synthesis, cell differentiation, and metabolic processes, while the expression of MAPK/ERK target genes remained unperturbed.
创建时间：
2024-01-16
