Additional file 2 of Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss

Additional file 2: Supplementary Table 1. Alignment details for raw RNA-seq and ChIP-seq data used in this study. Supplementary Table 2. Gene Set Enrichment Analysis significant (p<0.05, FDR<0.25) results obtained from pairwise sample comparisons. Categories mentioned in the manuscript are highlighted in bold. Supplementary Table 3. Genes excluded from the final clustering analysis. Supplementary Table 4. Lists of “α-cell transitional genes” including gene cluster association capturing the main differences between α-cells at different stages after β-cell loss. Number of human pancreatic islet enhancers, and number islet transcription binding sites for five islet transcription factors, that were associated with the promoters of genes in clusters 1 to 5. Supplementary Table 5. Statistical tests for genes showed in Figure 4B. Supplementary Table 6. Number of cells counted for the quantifications presented in the manuscript figures.