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Molecular targets of proteasome inhibitor, bortezomib, on ATL cells. Homo sapiens

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NIAID Data Ecosystem2026-03-06 收录
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Adult T-cell leukemia (ATL) is a fatal neoplasia derived from HTLV-1 infected T lymphocytes exhibiting constitutive activation of NF-kB. To elucidate the complex molecular mechanism of anti-tumor effect of the proteasome inhibitor, bortezomib in ATL cells, we attempted to perform gene expression profiling. Keywords: dose response Overall design: Four ATL cell lines were cultured with or without bortezomib, then analysed.

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2007-10-09
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