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structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease Descriptor: (2S)-2-benzamido-4-methyl-pentanoic acid, 4-[(4-fluoro-2-methyl-3H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline, ATP-dependent Clp protease proteolytic subunit 1, ... Authors: Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. Deposit date: 2018-12-04 Release date: 2020-01-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.69212103413 Å) Cite: structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease To Be Published

《西地尼布(Cediranib)抑制结核分枝杆菌(Mycobacterium tuberculosis)ClpP1P2的结构学解析:靶向Clp蛋白酶的抗菌药物开发启示》 描述物:(2S)-2-苯甲酰胺基-4-甲基戊酸、4-[(4-氟-2-甲基-3H-吲哚-5-基)氧基]-6-甲氧基-7-[3-(吡咯烷-1-基)丙氧基]喹唑啉、ATP依赖型Clp蛋白酶蛋白水解亚基1(ATP-dependent Clp protease proteolytic subunit 1)…… 作者:Bao, R、Luo, Y.F、Zhu, Y.B、Yang, Y、Zhou, Y.Z 存库日期:2018-12-04 发布日期:2020-01-01 最后修改日期:2024-11-06 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率为2.69212103413 埃(Å) 引用:西地尼布抑制结核分枝杆菌ClpP1P2的结构学研究:靶向Clp蛋白酶的抗菌药物开发启示(待发表)
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2018-12-04
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