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RNA-seq comparison of bone marrow stem cells isolated from two genotypes WT and Ppm1dT/+

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https://www.ncbi.nlm.nih.gov/sra/ERP148483
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Ppm1d T/+ mice exhibit altered BM composition. The aim is to determine the molecular mechanisms possibly responsible for this alterations in sorted long-term hematopoietic stem cells isolated from bone marrow. Long-term HSCs (LT-HSCs sorted from 12-week-old WT and Ppm1DT/+ mice. The Ppm1dT/+ HSC transcriptome shows enrichment of MYC, mTOR compared to WT.
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2024-01-03
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