Akt signalling leads to stem cell activation and promotes tumour development in epidermis.

ChEBI2014-01-26 更新2026-07-21 收录

肿瘤发生机制

Akt信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-48522 数据链接链接失效反馈

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Akt signalling leads to stem cell activation and promotes tumour development in epidermis.

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2014-01-26

Gene expression profiling in mouse fibroblast tumors with overexpression of the homeoprotein SIX1

肿瘤发生机制

细胞衰老调控

Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results also show that SIX1 acts as a repressor of cell senescence, an antiproliferative response wit

NIAID Data Ecosystem110

Transcriptome changes following loss of Apc in the intestine. Mus musculus

肿瘤发生机制

Wnt信号通路靶基因

Nearly all colorectal cancers have dysregulated Wnt signalling, predominantly through the mutation of the Apc (Adenomatous Polyposis Coli) gene. Therefore it is of vital importance to elucidate the ke

NIAID Data Ecosystem40

Categories of biological processes altered in Tg(flk:RFP)is18/+ Pre-tumor and Tumor tissues.

肿瘤发生机制

差异基因表达分析

*DGE Group: Differential Gene Expression Group. Genes were grouped according to direction of change in expression level in Pretumor and Tumor tissue.Categories of biological processes altered in Tg(fl

Figshare2015-12-02 更新20

p53 amyloid formation induced cellular transformation and tumor formation in xenograft model

p53

肿瘤发生机制

p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.

NIAID Data Ecosystem50

OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks. OncoSig: a new algorithm for the accurate and systematic de novo prediction of Oncoprotein-centric Signaling networks

癌症信号网络

肿瘤发生机制

We introduce a new algorithm, OncoSig, to address the deficiencies of canonical pathways through the accurate, context-specific prediction of proteins representing both known and novel functional memb

NIAID Data Ecosystem30

Akt signalling leads to stem cell activation and promotes tumour development in epidermis.

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