Prior host-adaptation enhances infectivity of PlzA-deficient spirochetes.

NIAID Data Ecosystem2026-03-12 收录

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https://figshare.com/articles/dataset/Prior_host-adaptation_enhances_infectivity_of_PlzA-deficient_spirochetes_/14991318 数据链接链接失效反馈

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资源简介：

Prior host-adaptation enhances infectivity of PlzA-deficient spirochetes.

创建时间：

2021-07-15

PlzA-deficient spirochetes show increased infectivity in immunodeficient ( scid ) mice.

螺旋体感染

免疫缺陷小鼠模型

PlzA-deficient spirochetes show increased infectivity in immunodeficient (scid) mice.

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Inactivation of Genes for Antigenic Variation in the Relapsing Fever Spirochete Borrelia hermsii Reduces Infectivity in Mice and Transmission by Ticks

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媒介传播病原体

Borrelia hermsii, a causative agent of relapsing fever of humans in western North America, is maintained in enzootic cycles that include small mammals and the tick vector Ornithodoros hermsi. In mamma

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Evidence for the Contribution of Point Mutations to vlsE Variation and for Apparent Constraints on the Net Accumulation of Sequence Changes in vlsE during Infection with Lyme Disease Spirochetes

病毒基因变异

螺旋体感染

In the Lyme disease spirochetes, both the ospE and vlsE gene families have been demonstrated to undergo sequence variation during infection. To further investigate the mechanisms associated with the g

PubMed Central20

Borrelia PeptideAtlas: A proteome resource of common Borrelia burgdorferi isolates for Lyme community

病原体蛋白质组学

螺旋体感染

Lyme disease is a result from an infection by the spirochete Borrelia burgdorferi, and is the leading vector-borne disease in North America. Due to the genomic and proteomic variability of different

NIAID Data Ecosystem40

One or more RpoS-dependent gene products, independent of ospC , are required for spirochete's to penetrate into the hemolymph; see Figure S1 for spirochete burden analyses.

螺旋体感染

蜱传疾病研究

aHemolymph was collected from feeding nymphs 72 h post-placement and cultured in BSK-II. The denominator represents the total number of ticks analyzed. bCultures were monitored for the presence of spi

NIAID Data Ecosystem40

Prior host-adaptation enhances infectivity of PlzA-deficient spirochetes.

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