Ferulic acid (FERH) is known to exert leishmanicidal action against Leishmania (Leishmania) amazonensis. In this study, the ferulate anion (FER–) was intercalated into a layered double hydroxide (LDH)
In the present study a series of 34 synthetic ligustrazine-containing α, β-Unsaturated carbonyl-based compounds and oximes, recognized as anticancer compounds were assessed against protozoa of the Try
The 50% inhibitory concentrations (IC50) of MMV compounds, their haemolytic profile (HC50) and selectivity against the promastigotes and amastigotes of Leishmania donovani.
In silico prediction of antileishmanial activity using quantitative structure–activity relationship (QSAR) models has been developed on limited and small datasets. Nowadays, the availability of large