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Comprehensive Transcriptomic Analysis of BV2 Microglia Following TDP-43 Knockdown Versus Non-Silencing Control

ChEBI2025-07-21 更新2026-07-12 收录

神经退行性机制

胶质细胞转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15184 数据链接链接失效反馈

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资源简介：

Comprehensive Transcriptomic Analysis of BV2 Microglia Following TDP-43 Knockdown Versus Non-Silencing Control

应用场景：

创建时间：

2025-07-21

神经退行性机制

细胞应激通路

Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw

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Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

神经退行性机制

细胞特异性翻译组

Ubiquitous expression of ALS-causing mutations in superoxide dismutase 1 (SOD1) provoke non-cell autonomous paralytic disease. By combining ribosome affinity purification and high-throughput sequencin

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Peripheral nerve injury mediated by JEV strain NX1889 infection and impairment of Schwann cells

神经退行性机制

病毒性神经损伤

The original data supporting data for the manuscript:Liping Yang, Yanping Yuan, Qikai Yin, Xiaocong Li, Xue Kang, Qianqian Cui, et al. Peripheral nerve injury mediated by JEV strain NX1889 infection a

Figshare2025-08-15 更新20

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons

神经退行性机制

功能障碍研究

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]

神经退行性机制

胶质细胞功能研究

GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp

NIAID Data Ecosystem30

Comprehensive Transcriptomic Analysis of BV2 Microglia Following TDP-43 Knockdown Versus Non-Silencing Control

资源简介：

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