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RNA Seq analysis of e12.5 mouse pancreatic buds from control and Pdxcre; Gata4fl/fl;Gata6fl/fl; Tom mice

ChEBI2016-03-08 更新2026-07-12 收录

胰腺发育生物学

RNAi基因敲除

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-77083 数据链接链接失效反馈

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RNA Seq analysis of e12.5 mouse pancreatic buds from control and Pdxcre; Gata4fl/fl;Gata6fl/fl; Tom mice

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创建时间：

2016-03-08

胰腺发育生物学

单细胞转录组学

Pancreatic and duodenal homeobox 1 (PDX1) is crucial for pancreas organogenesis, yet the dynamic changes in PDX1 binding in human or mouse developing pancreas have not been examined. To address this k

NIAID Data Ecosystem70

A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets

胰腺发育生物学

单细胞转录组学

This scRNA-seq data is an integral part of a manuscript with the above title. Using computational methods, we were able to reconstruct a detailed branched trajectory reflecting pancreatic endocrine di

NIAID Data Ecosystem50

PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

胰腺发育生物学

基因功能验证

The homeobox factor PDX-1 is a key regulator of pancreatic morphogenesis and glucose homeostasis; targeted disruption of the PDX-1 gene leads to pancreatic agenesis in pdx-1(−/−) homozygotes. Pdx-1 he

PubMed Central2001-01-16 更新10

Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas. Mus musculus

Hippo信号通路

胰腺发育生物学

The Hippo signaling pathway has become recognized as a context-dependent regulator of cell proliferation, differentiation, and apoptosis in species ranging from Drosophila to human. In this study, we

NIAID Data Ecosystem50

Pancreatic endocrinogenesis multiome

胰腺发育生物学

细胞命运多组学分析

This is a slimmed and processed version of the pancreatic endocrinogenesis (E14.5, 15.5, 16.5) dataset published with "Mapping cells through time and space with moscot", Klein et al., 2024. The raw da

Figshare2024-08-26 更新20

RNA Seq analysis of e12.5 mouse pancreatic buds from control and Pdxcre; Gata4fl/fl;Gata6fl/fl; Tom mice

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