相关数据集
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiC_LpreB_Steadystate]. A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [HiC_LpreB_Steadystate]
A generic level of chromatin organization generated by the interplay between cohesin and CTCF suffices to limit promiscuous interactions between regulatory elements, but a lineage-specific assembly of
NIAID Data Ecosystem20
Cell-specific and spatio-temporal controls of the estrogen-responsive trefoil factor (TFF) locus activity.II.. Homo sapiens
Cell-specific transcriptional regulations exerted by the estrogen (E2) receptor alpha (ER) heavily rely upon timely and spatially coordinated processes. We engaged a comparative analysis of such dynam
NIAID Data Ecosystem10
A multiscale 3D chromatin architecture that controls development of the humoral immune system is assembled by IKAROS [Hi-C_HaCaT]
A generic level of chromatin organization generated by the interplay between cohesin and CTCF suffices to limit promiscuous interactions between regulatory elements, but a lineage-specific assembly of
NIAID Data Ecosystem00
Genome-wide maps of nuclear lamina interactions in AML12 cells upon Safb KD [DamID]
Eukaryotic chromosomes fold into topologically associating domains (TADs), which further gather in active (A) or inactive (B) genomic compartments. Here we show that Scaffold Attachment Factor B (SAFB
NIAID Data Ecosystem10
Regulation of somatic hypermutation by higher-order chromatin structure [PRO-Seq]
The generation of protective antibodies by somatic hypermutation (SHM) is essential for antibody maturation and adaptive immunity. SHM involves co-transcriptional mutagenesis of immunoglobulin variabl
NIAID Data Ecosystem00
