RNA-seq and RRBS datasets from hippocampal tissue collected from 4 week old control and iron deficient piglets.

Environmental insults during sensitive periods can affect hippocampal development and function, but little is known about the mechanisms through which neonatal iron deficiency results in long term cognitive deficits. A previously published study reported reduced hippocampal-dependent learning and memory in iron deficient neonatal piglets. To investigate this further, we assessed gene expression and DNA methylation patterns in hippocampal tissue obtained from control and iron deficient piglets at 4 weeks of age using RNA-seq and RRBS.