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Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci

NIAID Data Ecosystem2026-05-01 收录

自身免疫疾病基因调控

EB病毒与自身免疫风险

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE148396 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-10-23

自身免疫疾病基因调控

STAT1信号通路分析

Autoimmune regulator (AIRE) regulates promiscuous expression of tissue-restricted antigens in medullary epithelial cells (mTEC) of the thymus. To understand the diverse effects of AIRE, it is crucial

NIAID Data Ecosystem80

Role of RelB in Interferon Dependent and Indpendent Gene Regulation

自身免疫疾病基因调控

干扰素信号通路

To investigate the Gene dysregulation caused by loss of RelB and identify candidate genes driving the loss of RelB autoimmune phenotype Comparative gene expression profiling analysis of RNA-seq data f

NIAID Data Ecosystem40

Mechanistic dissection of dominant AIRE mutations in mouse models reveals evidence for AIRE auto-regulation [ATAC-seq]

自身免疫疾病基因调控

表观遗传学分析

Using mouse models of several recessive and putative dominant-negative patient mutations we were able to dissect the mechanisms that underlie the recessive and dominant-negative capacities of the corr

NIAID Data Ecosystem20

RNA-seq of ATF7ip-deficient T cells

Th17细胞

自身免疫疾病基因调控

RNA-seq performed in ATF7ip-deficient T cells reveals a defect in Th17 gene induction secondary to increased IL-2 T helper 17 cells (Th17) are critical for fighting infections at mucosal surfaces, how

NIAID Data Ecosystem50

Transcriptional profile in the colon in response to C. rodentium infection

结肠转录组

自身免疫疾病基因调控

The identification of Atg16L1 as a susceptibility gene has implicated antibacterial autophagy in the pathogenesis of Crohn's disease, a major type of inflammatory bowel disease (IBD). However, the rol

Alliance of Genome Resources30

Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci

资源简介：

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