The London Structural Biology Application for beam time, comprising groups from Birkbeck College, UCL, Kingston University and the Queen Mar

Our BAG comprises of groups from the School of Natural Sciences at Birkbeck and several UCL Research Departments with the core of the groups in the Biosciences Division. Research groups from Queen Mary University of London (QMUL) and Kingston University are joint co-applicants as they have strong links and collaborations with groups from Birkbeck/UCL. All groups share common interests in disciplines including structural, chemical, molecular and cell biology; using multidisciplinary and multiscalar approaches. All investigators, ranging from early-career research fellows to internationally-established senior academics, apply X-ray crystallography carried out mainly at our Wellcome funded facility at Birkbeck, as an essential method enabling: i) description of the atomic level mechanistic details of macromolecules and macromolecular machines, and ii) structure-based drug discovery, iii) interdisciplinary structural biology projects combined mainly with cryoelectron microscopy (cryo-EM).