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Characterisation of Grem1 wild-type and mutant murine pancreatic tumours

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE182143
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We performed RNA-seq analysis on Grem1 wild-type and Grem1-deleted pancreatic tumour tissues from Pdx1-Flp;KrasFSF-G12D;Trp53frt/frt (KPF) mice. We compared the transcriptome between these two groups of tumours with the aim to understand their molecular signatures and the relevance to human pancreatic ductal adenocarcinoma subtypes. Transcriptome profiles of Grem1 wild-type and Grem1-deleted tumours were generated by deep RNA sequencing, in five biological replicates (primary KPF murine pancreatic tumours).
创建时间:
2022-07-08
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