Univariate Cox regression analysis of 4-year progression-free survival and overall survival of 180 patients with age <70 y/o in relation to chemotherapeutic strategies.

a. only oral regimens: XELODA and UFUR groups;b. combined regimens: FOLFOX, XELOX, OXA then 5-FU and FL groups.Abbreviations: 4-y OS: 4-year overall survival; 4-y PFS: 4-year progression-free survival; 95% CI: 95% confidence interval; FL: 5-Fluorouracil (5-FU)/leucovorin; FOLFOX: mFOLFOX 6, 5-FU/leucovorin/oxaliplatin; LNR: the positive lymph node ratio of dissected lymph nodes; OXA: oxaliplatin; OXA then 5-FU: Oxaliplatin-based chemotherapy (less than 8 cycles of 5-FU/leucovorin/oxaliplatin or less than 6 cycles of oral capecitabine/intravenous oxaliplatin) followed by 5-FU-based chemotherapy (5-FU/leucovorin, oral tegafur-uracil/folinate calcium or oral capecitabine); P: probability value; RR: relative risk; UFUR: oral UFUR/LV, tegafur-uracil/oral folinate calcium (leucovorin); vs: versus; XELODA: oral capecitabine; XELOX: CapeOx, oral capecitabine/intravenous oxaliplatin; y/o: years old.