Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells

ChEBI2015-02-15 更新2026-07-21 收录

干细胞软骨分化

组织工程前体细胞

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-64752 数据链接链接失效反馈

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Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells

创建时间：

2015-02-15

ITGB1 promotes the chondrogenic differentiation of human adipose-derived mesenchymal stem cells by activating the ERK signaling

干细胞软骨分化

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In current study, we found that ITGB1 gene overexpression significantly elevated COL II (collagen II), aggrecan and SOX9 (SRY-Box 9) expression but suppressed COL I (collagen I) expression in hADSCs.

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It has been notoriously challenging for researchers in the fields of stem cell biology and regenerative medicine to robustly generate uniform populations of differentiated cells from human induced plu

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Human mesenchymal stem cells (hMSCs), residing in bone marrow as well as in the synovial lining of joints, can be triggered to differentiate toward chondrocytes. Thus, hMSCs harbor great therapeutic p

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Recapitulation of embryonic developmental events is receiving increasing recognition as a strategy to induce robust tissue regeneration. In this work, we aimed to explore the critical events of cartil

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Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells

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