Analysis of SOX2 overexpression in hESCs undergoing cardiac differentiation.. Homo sapiens

SOX2 downregulation is a pre-requisite for proper cardiac differentiation. This study was performed to reveal the neagtive effects of SOX2 on cardiac differentiation. Overall design: Total RNA was isolated in a time course manner, from differentiating in-vitro samples: (i) no doxycycline treated cells differentiated under standard cardiac differentiation conditions (II) 0.2ug/ml doxycycline treated cells differentiated under standard cardiac differentiation conditions