CA3D: A Monte Carlo code to simulate 3D buffered diffusion of ions in sub-membrane domains

Abstract CA3D is a simulation program, based on Monte Carlo techniques, which simulates the buffered diffusion of ions in the sub-membrane domain of cells. Two geometries of submembrane domains are considered. The first, a conical domain, applies to spherical cells with a locally uniform distribution of channels while the second, a cylindrical domain, is intended to model ciliar cells and presynaptic terminals. Other domains can be implemented in the code with ease. The entry of ions takes place throu... Title of program: CA3D Catalogue Id: ADNW_v1_0 Nature of problem The buffered diffusion of ions in the sub-membrane domain of cells is simulated by means of Monte Carlo methods. Two geometries of submembrane domains are considered. The first, a conical domain, applies to spherical cells with a locally uniform distribution of channels while the second, a cylindrical domain, is intended to model ciliar cells and presynaptic terminals. Other domains can be implemented in the code with ease. The entry of ions takes place through discrete entry points (channel por ... Versions of this program held in the CPC repository in Mendeley Data ADNW_v1_0; CA3D; 10.1016/S0010-4655(01)00144-8 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)摘要 CA3D是一款基于蒙特卡洛（Monte Carlo）技术的仿真程序，用于模拟细胞膜下区域（sub-membrane domain）内离子的缓冲扩散过程。该程序考虑了两类膜下区域的几何构型：其一为锥形区域（conical domain），适用于通道局部分布均匀的球形细胞；其二为圆柱形区域（cylindrical domain），用于建模纤毛细胞（ciliar cells）与突触前末梢（presynaptic terminals）。其余类型的区域亦可便捷地在代码中实现。离子通过离散入口点（discrete entry points，channel por ...）进入…… 程序名称：CA3D 目录编号：ADNW_v1_0 问题性质 本程序采用蒙特卡洛方法，仿真细胞膜下区域内离子的缓冲扩散过程。两类膜下区域的几何构型被纳入考量：其一为锥形区域，适用于通道局部分布均匀的球形细胞；其二为圆柱形区域，用于建模纤毛细胞与突触前末梢。其余类型的区域亦可便捷地在代码中实现。离子通过离散入口点（channel por ...）进入…… Mendeley数据中的CPC仓库内留存的该程序版本 ADNW_v1_0; CA3D; 10.1016/S0010-4655(01)00144-8 本程序源自贝尔法斯特女王大学馆藏的CPC程序库（1969-2019）