Emodin and coleon AL inhibit endothelial cell proliferation in vitro.

IC50 values (± SD) for emodin and coleon A lactone are shown for the inhibition of proliferation of both bovine aortic endothelial cells (BAEC) and mouse aortic endothelial cells (MAEC). For comparison, effects of 3 other anti-angiogenic compounds are shown (wortmannin, LY294002, and SU5416).

牛主动脉内皮细胞（BAEC）和鼠主动脉内皮细胞（MAEC）的增殖抑制IC50值（±标准差）以及emodin和coleon A内酯的抑制效果均予以呈现。为进一步对比，同时展示了三种其他抗血管生成化合物（wortmannin、LY294002和SU5416）的作用。