Gut microbiome in colitis male and female mice

The chronic colitis model of male and female mice was established by DSS (dextran sulfate sodium).The diversity and differences of gut microbiome in feces of ulcerative colitis and normal mice were identified by 16S rRNA high-throughput sequencing technology. The existing gene database was used to estimate the functional gene composition of the intestinal flora and the functional differences between the four groups.