Expression data from Saccharomyces cerevisiae upon honokiol treatment
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE94945
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资源简介：
Honokiol (HNK), one of the main medicinal components in Magnolia officinalis, possesses antimicrobial activity against a variety of pathogenic bacteria and fungi.S. cerevisiae is a model eukaryote used for investigating the cellular and molecular mechanisms of anti-fungal drugs. To explore the molecular mechanism of its anti-fungal activity, we determined the effects of HNK on the mRNA expression profile of Saccharomyces cerevisiae using a DNA microarray approach. Wild-type S. cerevisiae (BY4741) cells were treated with 12 μg/mL HNK for 2 h (or an equal volume of ethanol for controls) and for RNA extraction and hybridization on Affymetrix microarrays. Biological replicates: 2 control replicates, 2 HNK treated replicates.
创建时间：
2017-05-22
