Cryo-EM structure of a class T GPCR in active state
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Cryo-EM structure of a class T GPCR in active state Descriptor: Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. Deposit date: 2022-05-03 Release date: 2022-10-12 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
活性状态T类G蛋白偶联受体(G protein-coupled receptor, 简称GPCR)的冷冻电镜(Cryo-EM)结构
描述:内切葡聚糖酶H(Endoglucanase H)、2型味觉受体成员46(Taste receptor type 2 member 46)、内切葡聚糖酶H、2型味觉受体成员46、苦味味觉受体T2R46(Bitter taste receptor T2R46)、鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(O)亚基γ-2(Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2)、鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(T)亚基β-1(Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1)等
作者:Liu, Z.J、Hua, T、Xu, W.X、Wu, L.J
存放日期:2022-05-03
发布日期:2022-10-12
最后修改日期:2025-07-02
实验方法:电子显微镜法,分辨率3.01埃(Å)
引用文献:《人类苦味味觉受体TAS2R46的马钱子碱激活结构基础》,《科学》(Science),2022年,第377卷
创建时间:
2022-05-03



