Maggot extracts overcome cisplatin resistance of ovarian cancer cells by targeting HSP90AB1/IGF1R signaling. Maggot extracts overcome cisplatin resistance of ovarian cancer cells by targeting HSP90AB1/IGF1R signaling

To investigate the main mechanism underlying cisplatin resistance in ovarian cancer, A2780/CDDP and SKOV3/CDDP cell lines were treated with both maggot extracts and cisplatin. We then performed gene expression profiling analysis using data obtained from RNA-seq of A2780 and A2780/CDDP cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for A2780 and A2780/CDDP cell lines.