RMSE for each VRQoL task and overall VRQoL score.

Each value is calculated as the absolute difference between predicted VRQoL score and the actual VRQoL score in the testing dataset in the leave-one-out cross validation. RMSE: root mean of the squared prediction error, VRQoL: vision-related quality of life, VA (worse-eye): visual acuity of the eye with worse mean deviation (MD), VA (better-eye): visual acuity of the eye with better MD, MR: Multiple regression with VA (better-eye), VA (worse-eye) and MD of IVF (Integrated Visual Field) (**: p<0.05, *: p<0.01, in comparison with Random Forest, ten fold cross validation).