Reprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells

ChEBI2016-06-29 更新2026-07-12 收录

细胞重编程表观遗传学

造血分化潜能评估

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60924 数据链接链接失效反馈

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Reprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells

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2016-06-29

Cellular identity loss occurring during both iPS cells generation and malignant transformation can be followed using the somatic markers Thy1 and Bcl11b (ATAC-seq). Cellular identity loss occurring during both iPS cells generation and malignant transformation can be followed using the somatic markers Thy1 and Bcl11b (ATAC-seq)

细胞重编程表观遗传学

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细胞重编程表观遗传学

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As somatic cells are converted to iPSCs, their chromatin undergoes wide-ranging rearrangements that affect the ratio of euchromatin-to-heterochromatin, DNA methylation patterns and the regulation of e

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Global DNA methylation remodeling during direct reprogramming from fibroblast to neuron [MethylC-seq]. Global DNA methylation remodeling during direct reprogramming from fibroblast to neuron [MethylC-seq]

细胞重编程表观遗传学

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Direct reprogramming from fibroblasts to neurons induces widespread cellular and transcriptional reconfigurations. In this study, we characterized global epigenomic changes during direct reprogramming

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Different propensity in hematopoietic differentiation potential among distinct human pluripotent stem cell lines. Homo sapiens

造血分化潜能评估

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Lineage-specific differentiation potential varies among different human pluripotent stem cell (hPSC) lines. A stem cell bank may advice researchers on which hPSCs exhibit the highest differentiation p

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Reprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells

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