Microbiota-dependent trimethylamine-N-oxide unaffected after lean-pork consumption in omnivorous individuals: a dietary-guidelines based randomized controlled-feeding trial

This is a controlled feeding study to explore if the different types of meat have different effects on human gut microbiota and metabolomics. The majority of Americans practice a meat-based dietary lifestyle. We hypothesized that switching between chicken and pork meats within a nutritionally balanced diet would minimally impact gut microbiota composition, biogenic amine levels, and cardiometabolic health markers in healthy, non-diabetic adults.